I-Load by Pro Supps
I-LOAD, short for “Insulin Load”, was designed to increase insulin sensitivity, and force carbohydrates, amino acids, creatine, and other anabolic nutrients into muscle tissue.
Main benefits of I-LOAD™ Include:
* Increase amino acid uptake in muscle tissue
* Increase insulin receptor sensitivity
* Increase glycogen storage in muscle tissue
* Increase protein synthesis and DNA replication
* Increase potassium uptake
* Increase blood flow
* Decrease breakdown of protein
* Enhance nutrient partitioning
How important is Insulin for building muscle?
Insulin is the most powerful anabolic hormone in your body that has the ability to increase protein synthesis, inhibit protein breakdown, and transport glucose, amino acids and creatine into muscle tissue. Almost every amateur and professional bodybuilder is familiar with the power of insulin due to the powerful glycogen pump it can produce along with hyper-loading of nutrients post workout. In addition, insulin also has a huge nutrient-partitioning effect, driving food (and stored food energy) into building muscle instead of building fat. The challenge with using prescription insulin is that if you make one bad mistake it could cost you your life or put you into a coma. Not good. So the key here is to manipulate this powerful hormone without risking the dangerous side effects.
Why is insulin sensitivity important?
One of the key elements to managing the power of insulin (and maintaining health), is to increase one’s insulin sensitivity and also reduce the chance of becoming insulin resistance. A person who is “insulin resistant” has a hard time processing carbohydrates and their body releases a ton of insulin to get glucose into the resistant cells. This “resistance” is not a good thing, and over-production of one’s own insulin can lead to type 2-diabetes which can cause kidney failure, blindness, arterial disease and coronary heart disease. The key to an efficient, healthy body is to increase insulin sensitivity where the body doesn’t have to release a ton of insulin to get the glucose into the cell. Insulin sensitivity is partly genetic and varies with each individual, usually peaking highest in professionally trained athletes. Three of the best ways to increase insulin sensitivity is through resistance training, cardiovascular training and manipulating one’s diet. A moderate carbohydrate diet rich in Omega-3 fatty acids, fish oil and fiber can make a dramatic impact upon one’s insulin sensitivity. On the flip side, the low-carbohydrate, high-fat diets that have become popular lately can decrease insulin sensitivity. People should be very careful of these types of diets and limit their use to a maximum of 3 weeks at a time especially if muscle gain is one’s preferred goal.
How do I use I-LOAD™?
To feel the effects of a full-on glycogen pump, take (1-2) capsules with your pre-workout meal or shake. Meal or shake must contain at least 40-50 grams of carbohydrates per capsule. For increased amino acid & glucose uptake and speed recovery, take (1-2) capsules immediately post-workout with at least 40-50 grams of carbohydrates per capsules. Advanced users may take (1) additional capsule per day with acarbohydrate rich meal. Do not exceed 6 capsules per day unless you are facilitating pre-contest carb loading.
How does I-LOAD™ work?
There are quite a few supplements that can help increase insulin receptor sensitivity and also drive glucose from the blood and into the muscle cell. The Glut-4 receptor inside your cell is the nutrient “gate keeper” that opens or closes depending upon the amount of insulin that is present in the blood. I-LOAD™ was designed to open up the Glut-4 flood gates & pull glucose out of the blood and into the muscle. This helps your body work more efficiently and keeps insulin sensitivity at its maximum.
I-LOAD™ is not your simple ALA/chromium combination. Utilizing cutting edge science, I-LOAD™ uses the following powerful weapons to help keep insulin sensitivity at its maximum and store nutrients like no other product currently on the market:
Banaba Leaf Extract provides a blood sugar lowering effect similar to that of insulin. It induces glucose transport from the blood into body cells.Recently, researchers have isolated an active ingredient in the banaba leaf called corosolic acid, which was originally thought to be "the" bloodsugar regulating substance in the leaf. A study published in the journal Planta Medica in 2001 compared a whole-leaf extract of banaba with insulin in cell cultures. The researchers concluded that the whole herb has a glucose lowering effect. In other animal studies, administration of banaba leaf extract resulted in reduced weight gain, reduced triglyceride accumulation and reduced adipose tissue, with no changes in diet.
Originating from India, Gymnema Sylvestre is known as gur-mar, or "sugar destroyer." Scientists think its active ingredients (gymnemic acids) protect the cells of the pancreas from free radical damage, allowing them to regenerate and produce insulin more effectively. A recent Harvard study indicates the Gymnema lowers blood sugar levels in Type I and Type II diabetics. At King's College in London, a study stated that Gymnema acts by increasing cell permeability, therefore reducing insulin resistance. Studies have shown that gymnema can reduce glucose absorption from the intestine, help regulate blood sugar levels and lower the amount of glucose available to be stored as fat.
When gymnema leaf is placed directly on the tongue, it eliminates the sensation of sweetness. The leaves of Gymnema sylvestre perform two significant functions. First, they suppress blood glucose, especially after eating. Secondly, they are insulin tropic and promote insulin secretion. By this multi-pathway approach, Gymnema sylvestre proves a valuable aid in hyper-loading glucose into muscles.
Momordica 10:1 Extract
Bitter melon is the common name for Momordica charantia, also known as African cucumber, balsam pear and bitter gourd. The phytochemicals present in bitter melon suggest that there are multiple uses for this herb. Among the constituents in bitter melon, charantin is identified as an important agent for blood-sugar regulation. Charantin demonstrates hypoglycaemic (blood sugar lowering). The Momordica fruit contain insulin-like peptides, including one known as polypeptide P. In human studies, bitter melon demonstrates significant blood-sugarcontrol after food intake and overall blood sugar-lowering effects.
In a study published in the journal Chemistry & Biology- March 2008, a research team, headed by Dr. Mon-Jia Tan of the Chinese Academy of Sciences in Shanghai, concluded that bitter melon has potent anti-diabetes effects. In their study, Tan and colleagues isolated and described several compounds from bitter melon known as cucurbitane triterpenoids, and tested their effects on glucose (sugar) and fat metabolism in cells and in mice. When tested in muscle and fat cells, the researchers found the compounds stimulated the glucose receptor GLUT4 to move from the cell interior to the cell surface, thus promoting more effective glucose metabolism. Several of the tested compounds had effects comparable to those of insulin. Tests in mice of two of the compounds found that they promoted both glucose tolerance and fat burning, and one was particularly effective in promoting glucose tolerance in animals consuming high fat diets.
Momordica has been found to be just as effective as glibenclamide in reducing blood sugar levels (J Ethnopharmacol 2003; 88(1): 107-111). In fact, a large study at Harvard University Medical School concluded that mormodica is one of the best natural remedies for diabetes (Diabetes Care 2003; 26(4): 1277-1294). It appears that mormodica contains compounds similar in structure to insulin, which have the same effects in regulating blood sugar levels. There is evidence that mormodica can prevent the release of excess glucose into the bloodstream from the liver(Am J Health Syst Pharm 2003; 60(4): 356-359).
Chromium helps insulin transport sugar to the cells. Chromium works to make insulin more effective by "bridging" insulin to cell membranes,thus increasing the number of active insulin receptors, resulting in increased insulin sensitivity. The trace mineral chromium is found in skin, fat, muscle, brain and the adrenal glands. There is about 6 mg in each of us and it is important! Chromium absorption through the small intestine is very poor; so normally, a lot of it gets excreted in urine. People with diabetes excrete even more chromium than healthy people; and the loss of this vital nutrient makes it harder for their bodies to respond to insulin. Studies show that chromium supplements can help both Type I andType II diabetics control their blood sugar.
There are various forms of chromium suitable for human ingestion. The Polynicotinate form of chromium called "Chromium polynicotinate" is the most absorbable. Chromium polynicotinate is a unique molecule that binds chromium with niacin, a compound found in breast milk, which helps the body better absorb and process minerals.
Pro Supps I-Load
Serving Size: 1-2 Capsules
Servings Per Container: 30-60
Amount Per Capsule:
Hyper-Load Matrix™ 450mg
Banaba Extract (2% Corosolic Acid)
Gymnema Sylvestre (75% Gymnemic Acid)
Momordica 10:1 Extract
Cinnamon 4:1 Extract
Other Ingredients: Gelatin (Bovine), Magnesium Sterate (Less than 0.5%) FD&C Yellow #6, FD&C Red #3, FD&C Blue #1.
Suggested Use: As a dietary supplement, take 1 capsule 30 to 45 minutes prior to exercise with 1 serving of Karbolic™ or 50 grams carbohydrates. Advanced users may take 2 capsules with at least 2 servings of Karbolic™ or 100 grams of carbohydrates.
WARNINGS: Not for use by individuals under the age of 18 years. Do not use if pregnant or nursing. Keep out of reach of children. Do not consume this product if you have a medical condition and/or taking any prescription medication. Do not exceed recommended servings. Do not use this product if you are at risk or are being treated for high blood pressure, kidney, thyroid or psychiatric disease, anxiety, depression, seizure, enlarged prostate, or stroke. Before beginning any supplement or training program always consult a physician first.